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With a long history behind it, years of experience and thousands of users worldwide, Photoshop is, without a doubt, the industry standard when it comes to photo manipulation and graphic design. In fact, its popularity is so widespread that its name became a verb, much like Google. It is habitual to say that an image has been “photoshopped”, which in the urban dictionary means that it was edited or manipulated, no matter the image editor that was used. Photoshop's popularity relies on its versatility and its impressive feature set, which meets the requirements of professional photographers and artists, advertising specialists and graphic designers. Amazing results can be achieved once Photoshop’s capabilities are mastered and explored to their highest potential. Creativity and imagination are the only limits  Photoshop delivers a plethora of tools for image manipulation, while making no compromise on quality whatsoever. Its toolbox includes an overwhelming collection of image editing features both for raster images and vector graphics. As expected with such a powerful and comprehensive application, it requires time, exercise, experimentation and practice to master, perhaps a significant amount of time spent watching tutorials and viewing usage examples to use at full potential. But once mastered, the rich graphics and the astounding images that can be obtained in Photoshop make it all worth it. Give your photos a stunning, eye-catching look  Layer-based editing is at the core of Photoshop, allowing image creation and manipulation using multiple overlays. Masks, filters, shadows and various other effects can be added to a layer. With smart auto-correction capabilities, HDR imaging, color management tools, tons of effects and animations, there is no editing task that Photoshop cannot carry out. It allows you to change picture backgrounds and fix imperfections, or use effects and colors to make a photo be much more eye-catching. It is not just editing tools that you have at hand, but also various drawing tools that bring you close to the real experience of painting in watercolor, spray-painting on a wall and achieve effects that you might not thought can be obtained in the digital world. Moreover, neural filters allow you to color a scene with a few clicks, combine landscapes to create collages or a new scenery and change face expressions in your photos. And, if that is not enough, the application’s functionality can be further extended using new plugins available both inside the application and in Creative Cloud. Presenting the Photoshop family  It is worth mentioning that the Photoshop family includes mobile tools that work together to provide a comprehensive and unmatched image manipulation suite. Photoshop Lightroom offers powerful image editing tools, Photoshop Express is the mobile Photoshop client that can be used on the go, while the Photoshop Camera is an app that allows capturing high-quality photos. Needless to say, Photoshop seamlessly integrates with other of Adobe’s products, allowing you to import content from Illustrator, for instance. The go-to image editing and manipulation software   Photoshop is the emblematic application when it comes to photo editing, managing to challenge your creativity and design skills, while providing the tools and the functionality needed to obtain incredible art and amazing graphics. Thanks to its clever selection tools, its professional-grade editing toolbox and its team collaboration and sharing options, Photoshop’s recognition as the industry standard has, indeed, a solid foundation.







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The Elements Adobe’s Photoflower (), Create It (), and Elements () are its free graphic design applications for people who are just getting into the digital photo editing business. Use any of these programs to produce the image you see on the following pages. Just be sure to try to manipulate the images as much as possible to gain insights into how digital image manipulation can work. The more you do, the better you’ll get at it. Here is a quick introduction to how all three programs work: 1. **Photoflower** is great for beginners who want to create graphics, photography, and videos. It allows you to edit existing photos or to take a new picture and then edit it. 2. **Create It** is for people who want a little more power, but it doesn’t offer as much customization as Photoflower or Elements. 3. **Elements** is for professionals who need a full-blown version of Photoshop, including layers and other more advanced editing tools, though it lacks the organic feel of the other two programs.

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While many people use Photoshop Elements to edit images, there are some people who also use it to create graphics, such as lettering, logos, icons, and posters. Adobe Photoshop Elements is great for all of these uses. Today, I will show you how to use Adobe Photoshop Elements to make logos and lettering. Whether you are looking to make a logo or if you need to make a letter for a project, I have a great resource for you. If you are having trouble choosing the logo design that’s right for you, check out these 20+ logo concepts. Best logo and illustration software and online tools that cover all of your needs to create a professional logo and illustration. I’ll also show you how to make a rough sketch to start the design process. You can always make changes later on. Let’s get started. Download the image files below. I used Adobe Photoshop Elements 11.0 for the logo design project, but you can use any version that you have. UPDATE – Since this tutorial was published, the file sizes have significantly increased. So if you didn’t already download the.PSD files from the Google Drive link above, you might want to do that now. You can also download the.AI files below. I recommend using the 900×900 resolution files instead of the smaller.PSD files. Let’s get started. Step 1: Set the Background and Color Scheme Image 1 – Click here to download the.PSD file First thing you will want to do is change the Background from White to Black. Go to Image > Mode > Black & White. In the Layers Panel, click on the Background layer. Image 2 – Click here to download the.PSD file Go to Image > Adjustments > Curves and check the boxes to highlight the Lighter and Darker areas. Now we can start to add color to the logo. Step 2: Create the Lines Image 3 – Click here to download the.AI file Create a new layer above the Background layer and use a very soft brush to paint over the White. Be careful with your brush settings. You don’t want the brush to be too hard. Soft brushes allow you to fill the creases and lines in the image without breaking them. Using a a681f4349e

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PrideFest 2019 The second annual PrideFest will be held on the evening of Saturday 19 September 2019 at The Lamell, Liverpool 7pm–Midnight. Tickets are now on sale and more details can be found here. LGBT History – Pride and Commissioning One of the first places the idea of a gay and lesbian festival was discussed was at the 1965 Convention of the National Union of Public Service Employees. At the time, it was accepted by all that a gay and lesbian festival was not within the remit of a trade union. However, as more organisations recognised the increasing growth of gay and lesbian related issues they became more open to the idea. It was only in 1995 when the World Pride Committee was established that it became a biennial event, which it remains to this day. The Campaign In the late 1970s and early 1980s, Peter Tatchell started lobbying politicians, community groups, politicians and the media to include lesbian, gay and bisexual rights within the public agenda. The campaign began to gain momentum when the Tom Mclennan case was decided in 1984. Tom Mclennan had been sentenced to two years in prison for a night of camping at Greenham Common. The sentence was upheld and appealed by gay and lesbian groups on the grounds of discrimination, which resulted in a judicial review in 1986. This decision gave the government a chance to review the law and in 1988, Peter Tatchell and two other men won their appeal and were awarded damages to be paid to them by the government. This was the first time that a British government had been ordered by the UK courts to pay damages for discrimination against gay people. This breakthrough was followed by the equalisation of the age of consent for gay and lesbian sex in 1998 and the legalisation of same-sex marriage in 2004, along with increased visibility for gay and lesbian people by advertising campaigns, documentaries and films. 2001 saw the launch of the Coalition for Equal Marriage rights. The coalition brought together gay rights groups, religious groups, and other LGBTQ advocates and organisations to promote a unique opposition to same-sex marriage. The campaign was highly successful and led to the British House of Commons passing a resolution supporting same-sex marriage with a majority vote of 237 to 35. The passing of this resolution caused a massive public response from gay and lesbian groups in the UK. Pride was first held in London in 1989 and the city was listed as a City of Refuge in the first ever report of the Runnymede Trust.

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Background {#s1} ========== Aflatoxins are secondary metabolites of certain fungi that can occur naturally in food. The aflatoxins B1, B2, G1 and G2 and aflatoxicosis are potentially harmful to human health. Aflatoxin B1 is a strong hepatotoxic and mutagenic compound. In recent years it has been proven that aflatoxin ingestion by animals is associated with an increase in relative liver weight and in particular with cirrhosis of the liver \[[@R01]–[@R03]\]. Like many other fungal metabolites, the oxides of aflatoxins are able to convert selenium to selenate. This in turn is toxic to the liver because it acts as an inhibitor of glutathione peroxidase \[[@R04]\]. Selenium is an essential nutrient required for the detoxification of toxic metabolites, since it participates in the catalytic cycle of the selenium-containing enzymes glutathione peroxidase and thioredoxin reductase. Selenium deficiency would increase the susceptibility of animals to toxic compounds. So, the aim of the present work was to evaluate the protective action of Se on aflatoxicosis in animal liver. Methodology {#s2} =========== **Se Treatment**: Male rats were divided in two groups: control and Se treated. The Se group was treated with sodium selenite 50ppm/kg body weight (Kanto Chemical Co., Tokyo, Japan) for two weeks \[[@R05]\]. The control group received tap water instead of Se. The animals were anaesthetized, euthanized and blood was collected. The livers were excised and weighed. The livers were frozen at -20°C then subsequently at -80°C. The tissues were freeze-dried and homogenised in distilled water, and then extracted with an acetone and ethyl acetate mixture for 24h at room temperature. The extracts were centrifuged at 3000rpm for 10min. The organic layer was collected and evaporated at 35°C, followed by air-drying. The dried extract was dissolved in ethyl acetate and filtered through a Sep-Pak Plus C18 cartridge (Waters, Milford, MA). The eluate was dried under a stream of nitrogen at 40°C. The analysis was performed with a Agilent Technologies 7890/

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OS: Win XP / Vista / 7 / 8 / 10 Processor: Intel Core 2 Duo / AMD Athlon 64 X2 / AMD Athlon X2 / AMD Phenom II X3 Memory: 3 GB RAM or more Graphics: NVIDIA GeForce 8600 / ATI Radeon HD 2600 / ATI Radeon HD 3650 / ATI Radeon HD 4850 / Intel HD Graphics 3000 / AMD HD 6350 DirectX: Version 9.0c Hard Drive: 6 GB or more Additional

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